Mounjaro vs Wegovy: What’s the Difference & Which One is Right for You?

Mounjaro vs Wegovy: What’s the Difference & Which One is Right for You?

At LIVVE, we know how confusing it can feel when choosing the right treatment for weight management. Two of the most talked-about medications are Mounjaro (tirzepatide) and Wegovy (semaglutide). Both are effective, but they’re not the same. Here’s what you need to know.

How They Work

Medication
What it is
How it works
Mounjaro (tirzepatide)
Dual-acting medication (targets GLP-1 & GIP receptors)
Helps regulate blood sugar, slows digestion, reduces appetite, and may support greater weight loss compared to single-acting drugs.
Wegovy (semaglutide)
GLP-1 receptor agonist
Mimics your body’s natural GLP-1 hormone to reduce appetite, slow digestion, and support weight loss.

Key Differences

  • Mechanism: Mounjaro acts on two pathways (GLP-1 + GIP), while Wegovy acts on just GLP-1.
  • Effectiveness: Early studies suggest Mounjaro may support greater weight loss, but both are clinically proven.
  • Cardiovascular benefit: Wegovy has been shown to reduce the risk of major cardiovascular events (such as heart attack or stroke) in people living with obesity and existing heart disease.
  • Dosing: Both are weekly injections, but with different titration schedules.

Who is Eligible? (NICE criteria)

To be prescribed Wegovy or Mounjaro privately in the UK, patients usually need to meet:

  • BMI ≥ 30 (obese), or
  • BMI ≥ 27 with a weight-related condition (e.g. type 2 diabetes, high blood pressure, high cholesterol, sleep apnoea).


Price Comparison (Private Prescriptions at LIVVE)

(Prices shown per pen, September 2025)

Strength
Mounjaro (tirzepatide)
Wegovy (semaglutide)
Starter dose
£205.00
£185.00
Mid-range dose
£215.00
£185.00
Higher dose
£285.00
£235.00
Top dose
£305.00
£250.00

(Prices include medication, consultation and postage)

Thinking About Switching?

If you’re currently on Mounjaro and worried about price changes, or if you’re considering moving from Wegovy to Mounjaro, it’s important to:

  1. Review with a LIVVE clinician - not all patients are suited to switching.
  2. Check your medical history & BMI - eligibility criteria must be met.
  3. Start from the lowest dose - even if switching, titration is important for safety.

The LIVVE Approach

We’ll always help you understand your options, weigh up the costs, and make the safest, most effective choice for your health.

  • Video consultation with a Specialist Pharmacist – personalised discussion about your health, treatment options, and next steps.
  • Tailored dietary advice – practical support to help you eat well and maximise your results.
  • Goal-focused care – we’ll guide you through your treatment and continue to support you once you’ve reached your target weight/health goals.
  • Ongoing support from our nutritionists & dietitians – referral to expert input to keep you on track and help you build sustainable, healthy habits.

Please note: We have now switched to include postage in all our prices. We are no longer able to offer a collect-from-store service this change allows us to dedicate more of our time to caring for patients and growing the LIVVE service.


Ready to talk it through?

Get personalised advice from the LIVVE team to find what’s right for you.

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