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TWICE-WEEKLY PRESCRIPTION OESTROGEN PATCHES
An oestrogen-only patch changed twice weekly to help relieve menopause symptoms, available in four prescribed strengths with clinical guidance at every stage.
Evorel contains estradiol and delivers oestrogen through the skin. It is not suitable for everyone and is prescribed only after a clinical assessment of your symptoms, medical history, bleeding pattern, current medicines and wider HRT plan.
Available in 25, 50, 75 and 100 micrograms/24 hours
Changed twice each week
Clinician-selected strength
Progesterone guidance where needed
Support with side effects or unexpected bleeding
Ongoing HRT reviews and dose adjustments when needed
QUICK PRODUCT FACTS
Key information about the medicine, available strengths and where it may fit within an HRT plan.
Medicine type
Oestrogen-only patch
Active ingredient
Estradiol
Available strengths
25, 50, 75 and 100 micrograms/24 hours
How often?
Changed twice weekly
Pack size
8 patches
Contains progesterone?
No
Prescription needed?
Yes
Review
Regular HRT review
Available strengths and prices
Each strength uses the same twice-weekly patch format. The difference is the amount of estradiol released over 24 hours.
| Strength | Estradiol released | Pack | LIVVE price |
|---|---|---|---|
| Evorel 25 | 25 micrograms per 24 hours |
8 patches |
£10 |
| Evorel 50 | 50 micrograms per 24 hours |
8 patches |
£11.50 |
| Evorel 75 | 75 micrograms per 24 hours |
8 patches |
£12 |
| Evorel 100 | 100 micrograms per 24 hours |
8 patches |
£13 |
A higher strength is not automatically better. Your clinician will prescribe the lowest effective strength that controls symptoms while remaining suitable and tolerable. Do not move between strengths or use more than one patch unless this is specifically included in your prescription.
How-to video guide
Watch before applying your first patch. The video will show where to place Evorel, how to prepare the skin, how to press the patch into place, when to change it and how to rotate application sites.
Video coming soon
How to apply your Evorel patch
Choose two regular change days, three or four days apart, and keep the patch on continuously between changes.
Remove the old patch before applying the new one.
Open the pouch only when you are ready and apply the patch straight away.
Choose clean, dry, cool, healthy and preferably hair-free skin on the trunk below the waist, such as the lower abdomen or buttocks.
Do not apply on or near the breasts, on damaged or irritated skin, in a skin fold, at the waistline or where tight clothing may rub.
Do not use cream, moisturiser, lotion, oil, gel, talc or powder on the area before applying the patch.
Avoid touching the sticky surface. Smooth the patch on without wrinkles and press firmly with the palm of your hand for at least 10 seconds, especially around the edges.
Use a different area each time and leave at least one week before using exactly the same site again.
You can normally bathe, shower, swim and exercise while wearing Evorel. Avoid scrubbing the patch and keep it covered from direct sunlight.
If adhesive remains after removal, gently rub it away or use soap and water; a small amount of baby oil may also help.
Always follow the dispensing label and patient information leaflet supplied with your patches. Contact LIVVE if any step is unclear.
WHAT IS EVOREL?
Evorel contains estradiol, an oestrogen that replaces some of the hormone that falls during perimenopause and menopause.
The patch releases estradiol steadily through the skin into the bloodstream. It is worn continuously and changed twice a week.
Your clinician will recommend a strength based on your symptoms, medical history, previous HRT and response to treatment. Your dose can be adjusted if needed.
What to expect
Everyone responds differently. Evorel starts delivering oestrogen through the skin once it is applied, but improvements in menopause symptoms can be gradual. Using your patches consistently is important when judging how well your treatment is working.
Focus on getting used to applying your patch and establishing your two regular change days each week. Some side effects, such as breast tenderness, headache, skin irritation or changes in bleeding, can occur when using HRT.
You may begin to notice an improvement in menopause symptoms during the first few weeks of treatment. Hot flushes and night sweats may become less frequent or less intense.
If your symptoms are still not well controlled, or you are experiencing side effects, your treatment can be reviewed. Your clinician will consider how you are responding before deciding whether any change is needed.
Sometimes the right next step is to continue with the same strength and allow more time. At other times, your clinician may recommend adjusting your strength, reviewing your progesterone or progestogen, or considering another form of HRT.
YOUR LIVVE PATHWAY
We keep the process clear so you understand your route, dose and progesterone plan before treatment begins.
Tell us about symptoms, periods, menopause stage, medical history and treatment preferences.
Your clinician considers whether patches, gel, spray or tablets are most appropriate.
If suitable, your patch strength and any required progesterone are prescribed.
You will receive guidance on starting treatment, access to LIVVE if side effects or bleeding concern you, and reminders when your HRT review or repeat prescription is due.
Dose and routine
Use Evorel exactly as prescribed and follow the leaflet for the approved application areas.
The aim is the lowest effective strength that controls your symptoms
Evorel is available in four strengths, but treatment is not a progression through every option. Your clinician will recommend a strength based on your symptoms, previous HRT, medical history and individual treatment plan.
Start with your prescribed strength
Use the exact Evorel strength shown on your dispensing label and change your patch twice a week on your usual change days.
Give your treatment time to work
Some menopause symptoms may begin to improve within the first few weeks. Your response can then be reviewed to decide whether your current strength is right for you.
Review symptoms and side effects
Your clinician will consider how well your symptoms are controlled, any side effects, bleeding pattern, skin reactions and how you are getting on with your overall HRT plan, including progesterone or another progestogen where needed.
Your strength can be adjusted
You may stay on the same strength, or your clinician may recommend increasing or reducing it depending on your response to treatment. Do not change strength, add extra patches or alter your dose yourself unless your clinician has advised you to.
Safety first
Your LIVVE clinician will review your symptoms, medical history, bleeding pattern, previous treatment and whether progesterone is needed before recommending Evorel.
Do not change your patch strength or use additional patches unless your clinician has advised you to.
Understanding womb protection
Evorel 25, 50, 75 and 100 contain oestrogen only. If you still have your womb, you will normally need progesterone or another progestogen to protect the womb lining.
If you have had your womb removed, progesterone is often not needed, although your clinician will confirm what applies to you.
Separate progesterone or progestogen
Options may include Utrogestan, Gepretix, Nalvee or another clinically appropriate medicine.
Hormonal coil
A suitable progestogen-releasing coil may sometimes provide womb protection.
Combined patch regimens
Evorel Conti contains oestrogen and progestogen in every patch. Evorel Sequi alternates two weeks of oestrogen-only Evorel 50 with two weeks of Evorel Conti in each 28-day cycle.
Changing treatment
Do not change your patch strength or use additional patches unless your clinician has advised you to.
A LIVVE clinician can help you compare patches, gel, spray and tablets and recommend the route and progesterone plan that best fits you.
This page is for information only and does not replace individual medical advice. Evorel is a prescription-only medicine and is supplied only if clinically appropriate after assessment. Always read the patient information leaflet and follow your prescriber’s instructions.
