A tablet may feel simpler, but it is still medical treatment.
Foundayo avoids injections and can be taken without fasting. It still requires careful assessment, gradual dose increases, side-effect support and ongoing clinical review.
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A new non-injectable weight-management option
A once-daily prescription tablet that can help reduce hunger, increase fullness and support weight management, without an injection or a strict fasting routine.
Foundayo contains orforglipron. It is prescribed only after an assessment of your health, current medicines, weight history and treatment goals. Foundayo is authorised in the UK and comes in six strengths.
One tablet each day
Six-step dose pathway
No food or water restrictions
Clinician-approved dose changes
No injection required
Ongoing weight and health reviews
Quick product facts
The essentials, followed by more detail on eligibility, dosing, administration and safety.
Active ingredient
Orforglipron
Medicine type
GLP-1 receptor agonist
How often?
Once daily
How is it taken
Whole, with or without food
Starting strength
0.8 mg
Maximum strength
17.2 mg
Prescription needed?
Yes
UK Status
Prescription only
Daily dose progression
The dose is increased gradually to help your body adjust. Take only the strength prescribed for you and never combine tablets to create a higher dose.
| Strength | Typical place in pathway | Minimum time at dose | LIVVE price |
|---|---|---|---|
| 0.8 mg | Starting dose |
At least 30 days |
£99 |
| 2.5 mg | Next dose step |
At least 30 days |
£119 |
| 5.5 mg | Further dose step |
At least 30 days |
£139 |
| 9 mg | Further dose step |
At least 30 days |
£159 |
| 14.5 mg | Higher dose step |
At least 30 days |
£179 |
| 17.2 mg | Maximum daily dose |
Ongoing, with review |
£199 |
Not everyone needs the maximum dose. Dose increases depend on treatment response and tolerability. A lower dose may remain appropriate for longer.
Do not use trial capsule doses to calculate your tablets. Clinical trials used capsule strengths that are not substitutable milligram for milligram with the UK film-coated tablets.
Eligibility and clinical assessment
It may be considered for adults living with obesity, or some adults living with overweight alongside a weight-related health condition. Suitability still depends on your wider health, medicines and individual treatment goals.
Your BMI, previous weight-management attempts and weight-related health risks are considered.
Your clinician reviews diabetes, diabetic eye disease, digestive conditions, gastroparesis, gallbladder problems, kidney or liver problems, pancreatitis and other relevant risks.
Some medicines affect orforglipron levels or require additional monitoring, dose limits or changes.
Foundayo is not used during pregnancy or breastfeeding and must be stopped before a planned pregnancy.
Oral hormonal contraception may be less effective after starting Foundayo and after each dose increase.
Your plan should focus on health, function and sustainable progress rather than a promised amount of weight loss.
How Foundayo works
Orforglipron acts on GLP-1 receptors and works on areas of the brain involved in appetite. It can help you feel fuller for longer, reduce hunger and make cravings easier to manage.
It also delays stomach emptying, which can contribute to fullness but may cause digestive side effects, particularly while the dose is increasing.
It should not remove the need to eat. Regular, nourishing meals, adequate protein and enough fluid remain important.
Dose progression
Treatment starts at 0.8 mg once daily. Any increase takes place only after at least 30 days and when clinically appropriate.
Begin at the licensed starting dose and learn how your appetite and digestion respond.
After at least 30 days, the dose increases to 2.5 mg once daily.
Your clinician considers side effects, appetite, nutrition, weight progress and other medicines.
Further licensed steps are 5.5 mg, 9 mg, 14.5 mg and 17.2 mg.
The aim is an effective, tolerable dose rather than reaching the maximum automatically.
Ongoing reviews consider benefit, side effects, adherence, nutrition and longer-term goals.
Taking your tablet
A consistent time can help. Foundayo does not require a fasting routine, but taking it at a similar time each day may make it easier to remember.
Take it at any time of day.
Take it with or without food.
No specific water restriction is required.
Swallow the tablet whole.
Do not break, crush or chew it.
Do not combine tablets to create a higher dose.
Do not take more than one tablet in a day.
Side effects and safety
Digestive side effects are common, particularly while the dose is increasing. They are often mild or moderate, but persistent or severe symptoms need clinical advice.
Common effects
Nausea, constipation, diarrhoea, vomiting, indigestion and abdominal pain are among the most commonly reported effects.
Contact LIVVE
Speak to the team if symptoms persist, worsen, affect eating or drinking, or make it difficult to use treatment safely.
Seek urgent help
Get urgent advice for severe persistent abdominal pain, serious dehydration, a severe allergic reaction, sudden vision changes or other rapidly worsening symptoms.
Tell LIVVE about severe digestive problems or gastroparesis. Orforglipron has not been studied in severe gastrointestinal disease and should be used with caution.
Do not increase the dose because weight loss has slowed. Treatment response, side effects, nutrition, other medicines and wider health should be reviewed before changes.
Supporting healthy weight loss
A good programme is about more than eating less. LIVVE should help you maintain nourishing intake and habits that can continue beyond medication.
Protein
Include a useful source at meals to support muscle maintenance and recovery.
Fibre
Increase gradually alongside fluid to support bowel health and manage constipation.
Hydration
Drink regularly, especially if you experience vomiting or diarrhoea.
Strength and movement
Combine regular activity with resistance exercise where appropriate for your health and ability.
Your LIVVE pathway
Foundayo is prescribed following a clinical assessment to make sure treatment is appropriate for you. If suitable, your LIVVE clinician will support you with prescribing, dose changes and ongoing review.
Tell us about your health, medicines, contraception, weight history, previous treatments and goals.
A LIVVE clinician checks eligibility, safety, medicine interactions and whether Foundayo may be appropriate.
If approved and stock is available, the prescribed strength is dispensed with clear instructions.
Reviews cover appetite, side effects, adherence, nutrition, weight progress and dose suitability.
Choosing a treatment format
A flexible tablet routine may suit some people, while others may prefer a weekly treatment. Your clinician can help you compare the practical and clinical differences.
| Option | Format | How it fits |
|---|---|---|
| Foundayo tablets | Once-daily oral orforglipron tablet | No injection, fasting period or food restriction is required. |
| Wegovy® tablets | Once-daily oral semaglutide tablet | No injection is required, but a strict fasting, water and waiting routine must be followed. |
| Wegovy® injection | Once-weekly semaglutide injection | May be discussed if it better suits your health, preferences or previous treatment. |
| Mounjaro® injection | Once-weekly tirzepatide injection | May be discussed if it better suits your health, preferences or previous treatment. |
Start with a clinical assessment. LIVVE can help you understand whether oral orforglipron may be appropriate and whether its daily routine is suitable for you.
Medical disclaimer: This page is for information only and does not replace individual medical advice. Foundayo is a prescription-only medicine supplied only after assessment and approval by an appropriate prescriber. Eligibility, prescribing, supply and dose changes are subject to clinical suitability. Always read the patient information leaflet and follow your dispensing label and clinician's instructions. Seek urgent medical help for severe or concerning symptoms.